RECRUITING

The Venous Distension Reflex and Orthostatic Hypertension

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).

Official Title

The Venous Distension Reflex and Orthostatic Hypertension

Quick Facts

Study Start:2020-03-10
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03496792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Are capable of giving informed consent
  2. * Are of any race or ethnicity
  3. * Are fluent in written and spoken English
  4. * Whose history and physical exam did not uncover any exclusion criteria
  5. * Are 18 years of age
  6. * Systolic BP (SBP) during standing is at least 10 mmHg \> the supine SBP
  7. * Patients with a diagnosis of stage I hypertension without other chronic diseases may be INCLUDED
  8. * The change in SBP by standing is within ± 5 mmHg from the supine SBP
  9. * Matched gender, similar age and BMI (within 10%) to participants with elevated standing BP
  10. * Free of acute or chronic medical conditions
  1. * Age \< 18 years of age
  2. * Are a pregnant or nursing woman
  3. * Are a prisoner or institutionalized individual or unable to consent
  4. * Have chronic diseases (e.g. heart, lung, neuromuscular disease, or cancer) other than stage I hypertension
  5. * Have orthostatic hypotension or a history of syncope
  6. * Current smoker
  7. * History of blood clots

Contacts and Locations

Study Contact

Jian Cui, PhD
CONTACT
717-531-1799
jcui@pennstatehealth.psu.edu
Kris Gray
CONTACT
717-531-4589
kgray1@pennstatehealth.psu.edu

Principal Investigator

Jian Cui
PRINCIPAL_INVESTIGATOR
Penn State College of Medicine

Study Locations (Sites)

Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033
United States

Collaborators and Investigators

Sponsor: Milton S. Hershey Medical Center

  • Jian Cui, PRINCIPAL_INVESTIGATOR, Penn State College of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-03-10
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2020-03-10
Study Completion Date2025-06-30

Terms related to this study

Keywords Provided by Researchers

  • venous distension reflex

Additional Relevant MeSH Terms

  • Blood Pressure