RECRUITING

Zinc Oxide Versus Petrolatum Following Skin Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this split scar, head to head study comparing zinc oxide and petrolatum. Patients will apply respective ointments to each half of scar daily for one month and maintain a log of these activities. They will be seen at 1 week, 4 weeks, 8 weeks, and 6 months post-operatively for photographic scar assessment and to complete the patient portion of the Patient and Observer Scar Assessment Scale (POSAS), a quantitative objective assessment of scar appearance. Trained observers (board-certified dermatologists) will score the observer portion of the scale. POSAS outcomes, post-operative infections, linear density of epidermal seal will be assessed at the 1 week, 4 weeks, 8 weeks, and 6 months post-operative periods and compared between the two groups. Participants will have parking validated for all visits and upon completion of all portions of the study will receive a standardized skin care gift bag containing samples for hypoallergenic skin care products (washes, moisturizers, etc.).

Official Title

Zinc Oxide Versus Petrolatum Following Skin Surgery: a Head-to-head, Prospective, Split-scar Study

Quick Facts

Study Start:2021-09-01
Study Completion:2025-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03561376

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. ≥ 18 years of age
  2. 2. Linear closure, non-scalp site
  3. 3. ≥ 4.5 cm in length (final incision/closure length)
  4. 4. End to end symmetry (surgical site is not grossly asymmetric from end to end)
  5. 5. Grossly uninfected site
  1. 1. ≤ 18 years
  2. 2. Visibly asymmetric linear scar
  3. 3. Grossly infected surgical site
  4. 4. History of allergy to topical zinc oxide

Contacts and Locations

Study Contact

Lauren Crow, MD
CONTACT
4126474279
crowld@upmc.edu

Principal Investigator

Lauren Crow, MD
PRINCIPAL_INVESTIGATOR
Resident Physician, PGY-3

Study Locations (Sites)

UPMC Dermatology St. Margaret
Pittsburgh, PA, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Lauren Crow, MD, PRINCIPAL_INVESTIGATOR, Resident Physician, PGY-3

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-01
Study Completion Date2025-09-30

Study Record Updates

Study Start Date2021-09-01
Study Completion Date2025-09-30

Terms related to this study

Keywords Provided by Researchers

  • Scar

Additional Relevant MeSH Terms

  • Surgical Incision
  • Surgery--Complications
  • Surgical Wound
  • Surgical Site Infection
  • Scar
  • Hypertrophic Scar