RECRUITING

Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Cigarette smoking is more prevalent (50-70%) in persons living with HIV in the U.S. when compared with the general population and is linked to increased rates of heart disease, lung diseases and infections, and lung cancers. Because of their high levels of nicotine dependence, low quit rates, and familiarity with harm reduction, HIV-positive smokers may view the use of alternative nicotine delivery products, such as electronic cigarettes (ECs), as an attractive option for reducing and eventually stopping combustible cigarette use. However, little is known about the health effects of electronic cigarette use in HIV-positive smokers. Some studies have shown that electronic cigarette use was associated with increased confidence to quit smoking in the general population. The primary objectives of this project are to examine whether HIV-positive smokers, who are unwilling or unable to quit smoking, will substitute an electronic cigarette for regular cigarettes, and to examine whether there are any changes in heart and lung health in HIV-positive smokers who switch from regular cigarettes to electronic cigarettes.

Official Title

Health Effects of the Standardized Research E-Cigarette for Harm Reduction in Smokers With HIV

Quick Facts

Study Start:2022-03-01
Study Completion:2024-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03862924

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * diagnosed with and engaged in care for HIV (defined as at least one HIV clinic medical appointment within the past six month period)
  2. * at least 18 years of age
  3. * smoke at least 5 cigarettes per day for longer than one year
  4. * exhaled carbon monoxide (CO) level greater than 5 at BL
  1. * intention to quit smoking in the next 30 days
  2. * currently using pharmacotherapy for smoking cessation
  3. * currently using electronic cigarettes more than 2 days/week
  4. * unstable medical or psychiatric condition (defined as hospitalization)
  5. * medical contraindications to nicotine (unstable angina, uncontrolled hypertension, or recent cardiovascular event, including hospitalization)
  6. * psychotic symptoms
  7. * substance use disorder other than nicotine dependence
  8. * past-month suicidal ideation or past-year suicide attempt
  9. * pregnant or nursing.

Contacts and Locations

Study Contact

PATRICIA A CIOE, PhD
CONTACT
401-863-6638
patricia_cioe@brown.edu
Jasmine DiLorenzo, BA
CONTACT
401-863-6645
jasminette_dilorenzo@brown.edu

Principal Investigator

PATRICIA A CIOE, PhD
PRINCIPAL_INVESTIGATOR
Brown University

Study Locations (Sites)

Brown University School of Public Health
Providence, Rhode Island, 02912
United States

Collaborators and Investigators

Sponsor: Brown University

  • PATRICIA A CIOE, PhD, PRINCIPAL_INVESTIGATOR, Brown University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-03-01
Study Completion Date2024-12-30

Study Record Updates

Study Start Date2022-03-01
Study Completion Date2024-12-30

Terms related to this study

Keywords Provided by Researchers

  • HIV
  • smoking

Additional Relevant MeSH Terms

  • HIV