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Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications

Description

This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy. Men who are in need of prostate biopsy due to clinical suspicions of prostate cancer will be randomly assigned (1:1) to either transrectal or transperineal approach. This research study will scientifically determine if one biopsy method is better than the other in reducing complications and improving cancer detection.

Study Overview

Study Details

Study overview

This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy. Men who are in need of prostate biopsy due to clinical suspicions of prostate cancer will be randomly assigned (1:1) to either transrectal or transperineal approach. This research study will scientifically determine if one biopsy method is better than the other in reducing complications and improving cancer detection.

Prospective, Randomized Study Comparing Transperineal and Transrectal Prostate Biopsy Efficacy and Complications (ProBE-PC Trial)

Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications

Condition
Prostate Cancer
Intervention / Treatment

-

Contacts and Locations

Albany

Albany Medical College, Albany, New York, United States, 12208

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * All patients who are scheduled to undergo prostate biopsy for suspected prostate cancer as part of their regular medical care
  • * Either with or without an MRI
  • * Patients with no access to rectum (due to previous rectal surgery)
  • * Any abnormalities of the perineal skin (e.g. infection)
  • * Patients whose procedure requires sedation or general anesthesia

Ages Eligible for Study

to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Albany Medical College,

Badar M Mian, MD, PRINCIPAL_INVESTIGATOR, Albany Medical College

Study Record Dates

2025-12-31