RECRUITING

IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.

Official Title

A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle

Quick Facts

Study Start:2019-05-10
Study Completion:2023-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04149496

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 38 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * PCO pattern with \> 25 antral follicles
  2. * AMH \> 3.5
  1. * BMI \> 35
  2. * body morphology making transvaginal retrieval difficult or impossible
  3. * complicating medical condition making pregnancy or IVF relatively contra-indicated

Contacts and Locations

Study Contact

Bruce I Rose, MD, PhD
CONTACT
904-260-0352
brose@brownfertility.com
Samuel Brown, MD
CONTACT
904-260-0352
sbrown@brownfertility.com

Principal Investigator

Bruce I Rose, MD, PhD
PRINCIPAL_INVESTIGATOR
Brown Fertility

Study Locations (Sites)

Brown Fertility
Jacksonville, Florida, 32256
United States

Collaborators and Investigators

Sponsor: Bruce Rose, MD

  • Bruce I Rose, MD, PhD, PRINCIPAL_INVESTIGATOR, Brown Fertility

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-05-10
Study Completion Date2023-12-31

Study Record Updates

Study Start Date2019-05-10
Study Completion Date2023-12-31

Terms related to this study

Keywords Provided by Researchers

  • IVM
  • in vitro maturation
  • polycystic ovarian syndrome
  • PCOS
  • Steiner-Tan needle
  • oocyte maturation

Additional Relevant MeSH Terms

  • Polycystic Ovary Syndrome