IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

Description

A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.

Conditions

Polycystic Ovary Syndrome

Study Overview

Study Details

Study overview

A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte environment during oocyte retrieval, use of oral medications and very low doses of FSH, and delayed embryo transfer during subsequent warmed cryo-preserved embryo transfer. Eligible patient have a PCO pattern in their ovaries during transvaginal ultrasound.

A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle

IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer

Condition
Polycystic Ovary Syndrome
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Brown Fertility, Jacksonville, Florida, United States, 32256

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * PCO pattern with \> 25 antral follicles
  • * AMH \> 3.5
  • * BMI \> 35
  • * body morphology making transvaginal retrieval difficult or impossible
  • * complicating medical condition making pregnancy or IVF relatively contra-indicated

Ages Eligible for Study

18 Years to 38 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Bruce Rose, MD,

Bruce I Rose, MD, PhD, PRINCIPAL_INVESTIGATOR, Brown Fertility

Study Record Dates

2023-12-31