RECRUITING

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascular and kidney disease in AIs of Southwestern US. The proposed CRIC ancillary cohort study of 500 AIs (AI-CRIC) will rapidly improve our understanding of both potential risk factors for CKD progression, as well as the scope of this disease among AIs. This study leverages the current CRIC study and incorporates the planned activities of the next phase of the study - "CRIC 2018" - by implementing contemporary CRIC protocols for kidney and cardiovascular measurement and outcomes.

Official Title

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Quick Facts

Study Start:2020-08-31
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04185844

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Glomerular Filtration Rate (GFR): eGFR of =\>61\<80 and microalbuminuria \> 30 or eGRF of =\<60 (no microalbuminuria required).
  1. 1. Unable or unwilling to provide informed consent
  2. 2. life expectancy \<3 years;
  3. 3. institutionalized subjects;
  4. 4. End stage renal disease or renal transplant;
  5. 5. renal cancer;
  6. 6. myeloma;
  7. 7. immunosuppression;
  8. 8. Polycystic kidney disease;
  9. 9. participation in any clinical trial,
  10. 10. current pregnancy
  11. 11. current incarceration.
  12. 12. Appears unlikely or unable to participate in the required study procedures as assessed by the investigator, study coordinator or designee.

Contacts and Locations

Study Contact

Mark L Unruh, MD
CONTACT
505-272-8300
MLUnruh@salud.unm.edu

Principal Investigator

Mark L Unruh, MD
PRINCIPAL_INVESTIGATOR
University of New Mexico

Study Locations (Sites)

NIDDK-Phoenix Epidemiology and Clinical Research
Phoenix, Arizona, 85016
United States
First Nations Community Health Source
Albuquerque, New Mexico, 87108
United States
Zuni Health Initiative Center
Black Rock, New Mexico, 87327
United States

Collaborators and Investigators

Sponsor: University of New Mexico

  • Mark L Unruh, MD, PRINCIPAL_INVESTIGATOR, University of New Mexico

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-08-31
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2020-08-31
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Diabetes Mellitus
  • Chronic Kidney Diseases
  • Heart Diseases
  • Cardiovascular Diseases