American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Description

Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascular and kidney disease in AIs of Southwestern US. The proposed CRIC ancillary cohort study of 500 AIs (AI-CRIC) will rapidly improve our understanding of both potential risk factors for CKD progression, as well as the scope of this disease among AIs. This study leverages the current CRIC study and incorporates the planned activities of the next phase of the study - "CRIC 2018" - by implementing contemporary CRIC protocols for kidney and cardiovascular measurement and outcomes.

Conditions

Diabetes Mellitus, Chronic Kidney Diseases, Heart Diseases, Cardiovascular Diseases

Study Overview

Study Details

Study overview

Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascular and kidney disease in AIs of Southwestern US. The proposed CRIC ancillary cohort study of 500 AIs (AI-CRIC) will rapidly improve our understanding of both potential risk factors for CKD progression, as well as the scope of this disease among AIs. This study leverages the current CRIC study and incorporates the planned activities of the next phase of the study - "CRIC 2018" - by implementing contemporary CRIC protocols for kidney and cardiovascular measurement and outcomes.

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Condition
Diabetes Mellitus
Intervention / Treatment

-

Contacts and Locations

Phoenix

NIDDK-Phoenix Epidemiology and Clinical Research, Phoenix, Arizona, United States, 85016

Albuquerque

First Nations Community Health Source, Albuquerque, New Mexico, United States, 87108

Black Rock

Zuni Health Initiative Center, Black Rock, New Mexico, United States, 87327

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Glomerular Filtration Rate (GFR): eGFR of =\>61\<80 and microalbuminuria \> 30 or eGRF of =\<60 (no microalbuminuria required).
  • 1. Unable or unwilling to provide informed consent
  • 2. life expectancy \<3 years;
  • 3. institutionalized subjects;
  • 4. End stage renal disease or renal transplant;
  • 5. renal cancer;
  • 6. myeloma;
  • 7. immunosuppression;
  • 8. Polycystic kidney disease;
  • 9. participation in any clinical trial,
  • 10. current pregnancy
  • 11. current incarceration.
  • 12. Appears unlikely or unable to participate in the required study procedures as assessed by the investigator, study coordinator or designee.

Ages Eligible for Study

21 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of New Mexico,

Mark L Unruh, MD, PRINCIPAL_INVESTIGATOR, University of New Mexico

Study Record Dates

2025-06-30