COMPLETED

Pain, Inflammation and Opioid Craving

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be randomized to one of two brief education sessions followed by an assessment of response to pain. Investigators will test the association between response to pain and opioid craving.

Official Title

Affective and Inflammatory Reactivity to Pain in Opioid Use Disorder

Quick Facts

Study Start:2021-05-04
Study Completion:2025-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04190563

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * age 18 years or older;
  2. * diagnosis of opioid use disorder
  3. * chronic pain
  4. * ability to read and provide informed consent
  1. * major psychiatric or medical condition that would interfere with participation
  2. * current opioid withdrawal
  3. * currently receiving opioid analgesic medication for pain
  4. * recent history of myocardial infarction or other serious cardiovascular condition
  5. * current peripheral neuropathy, active vasculitis or severe peripheral vascular disease
  6. * systematic inflammatory or autoimmune disorder
  7. * admitted to current treatment episode on an involuntary status

Contacts and Locations

Principal Investigator

Rebecca K McHugh, PhD
PRINCIPAL_INVESTIGATOR
Mclean Hospital

Study Locations (Sites)

McLean Hospital
Belmont, Massachusetts, 02478
United States

Collaborators and Investigators

Sponsor: Mclean Hospital

  • Rebecca K McHugh, PhD, PRINCIPAL_INVESTIGATOR, Mclean Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-04
Study Completion Date2025-07-31

Study Record Updates

Study Start Date2021-05-04
Study Completion Date2025-07-31

Terms related to this study

Additional Relevant MeSH Terms

  • Opioid-use Disorder