Pain, Inflammation and Opioid Craving

Description

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be randomized to one of two brief education sessions followed by an assessment of response to pain. Investigators will test the association between response to pain and opioid craving.

Conditions

Opioid-use Disorder

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Study Overview

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Study Details

Study overview

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be randomized to one of two brief education sessions followed by an assessment of response to pain. Investigators will test the association between response to pain and opioid craving.

Affective and Inflammatory Reactivity to Pain in Opioid Use Disorder

Pain, Inflammation and Opioid Craving

Condition
Opioid-use Disorder
Intervention / Treatment

-

Contacts and Locations

Belmont

McLean Hospital, Belmont, Massachusetts, United States, 02478

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * age 18 years or older;
  • * diagnosis of opioid use disorder
  • * chronic pain
  • * ability to read and provide informed consent
  • * major psychiatric or medical condition that would interfere with participation
  • * current opioid withdrawal
  • * currently receiving opioid analgesic medication for pain
  • * recent history of myocardial infarction or other serious cardiovascular condition
  • * current peripheral neuropathy, active vasculitis or severe peripheral vascular disease
  • * systematic inflammatory or autoimmune disorder
  • * admitted to current treatment episode on an involuntary status

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mclean Hospital,

Rebecca K McHugh, PhD, PRINCIPAL_INVESTIGATOR, Mclean Hospital

Study Record Dates

2025-07-15