RECRUITING

Reactive Balance Training for Fall Prevention

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this pilot study is to evaluate and compare the effect of three different perturbation based training devices on the reactive balance control among healthy young adults, healthy older adults, and neurologically impaired stroke individuals. Furthermore, the project aims to determine the feasibility and tolerability of 30-minutes of perturbation training using the SureFooted Trainer. Overall, the project directs to find out the long term effect of training on fall risk reduction and fall prevention. This study investigates the effects of perturbation training (slip and trip) based on the principles of motor learning. Perturbations in the form of slips and trips induced by the three different types of perturbation devices will displace the center of mass outside the base of support and challenge the stability, thereby inducing a fall and demand compensatory strategies in order to prevent it. Such perturbation training would train the motor system to improve stability control and vertical limb support. The project design aims to examine the ability of the central nervous system to mitigate the interference in stability control (if any) that is induced by opposing types of perturbations. The hypothesis of this study if supported by the results, will provide the difference in motor learning with training on three different perturbation devices. Furthermore, it would help to determine which of the three training devices is the most effective in developing defense mechanisms necessary to reduce fall-risk among community-living older adults and the neurological population.

Official Title

Reactive Balance Training for Fall Prevention: a Comparative Study of Three Different Perturbation Devices

Quick Facts

Study Start:2018-02-01
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04205279

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age group: 18-55 years.
  2. * Absence of any acute or chronic neurological, cardiopulmonary, musculoskeletal or systemic diagnosis.
  3. * No recent major surgery (\< 6 months) or hospitalization (\< 3 months)
  4. * Not on any sedative drugs.
  5. * Can understand and communicate in English
  6. * Age group: 56-90 years.
  7. * Absence of any acute or chronic neurological, cardiopulmonary, musculoskeletal or systemic diagnosis.
  8. * No recent major surgery (\< 6 months) or hospitalization (\< 3 months)
  9. * Not on any sedative drugs.
  10. * Ability to walk with or without an assistive device for 10 meters
  11. * Can understand and communicate in English
  12. * Berg balance scale score \<45/56.
  13. * Age group: 18-90 years.
  14. * Absence of any acute or chronic neurological diagnosis except stroke (self reported)
  15. * Onset of stroke (\> 6 months)
  16. * Absence of any cardiopulmonary, musculoskeletal or systemic diagnosis.
  17. * No recent major surgery (\< 6 months) or hospitalization (\< 3 months)
  18. * Not on any sedative drugs.
  19. * Ability to walk with or without an assistive device for 10 meters
  20. * Can understand and communicate in English
  1. * Subjects will not proceed with the test if any of the following occurs at baseline measurement: 1) HR \> 85% of age-predicted maximal heart rate (HRmax) (HRmax = 220 - age), 2) systolic blood pressure (SBP) \> 165 mmHg and/or diastolic blood pressure (DBP) \> 110 mmHg during resting), and 3) oxygen saturation (measured by pulse oximeter) during resting \< 95%.
  2. * Body weight more than 250 lbs.
  3. * Individuals with heel bone density with a T-score \< -2, is classified as osteoporotic and will be excluded.
  4. * Individuals with mild cognitive impairment (Mini-mental State Exam score \< 25/30) will be excluded.
  5. * Subjects will not proceed with the test if any of the following occurs at baseline measurement: 1) HR \> 85% of age-predicted maximal heart rate (HRmax) (HRmax = 220 - age), 2) systolic blood pressure (SBP) \> 165 mmHg and/or diastolic blood pressure (DBP) \> 110 mmHg during resting), and 3) oxygen saturation (measured by pulse oximeter) during resting \< 95%.
  6. * 6 minute walk test. Subjects will also be screened out if on the 6 minute walk test they complain of shortness of breath or uncontrolled pain (\> 3/10 on VAS) or pulse oxygen drops \< 92% or are unable to achieve the age-specified minimal ambulation distance.
  7. * Body weight more than 250 lbs.
  8. * Individuals with heel bone density with a T-score \< -2, is classified as osteoporotic and will be excluded.
  9. * Individuals with mild cognitive impairment (Mini-mental State Exam score \< 25/30) will be excluded.
  10. * Subjects will not proceed with the test if any of the following occurs at baseline measurement: 1) HR \> 85% of age-predicted maximal heart rate (HRmax) (HRmax = 220 - age), 2) systolic blood pressure (SBP) \> 165 mmHg and/or diastolic blood pressure (DBP) \> 110 mmHg during resting), and 3) oxygen saturation (measured by pulse oximeter) during resting \< 95%.
  11. * 6 minute walk test. Subjects will also be screened out if on the 6 minute walk test they complain of shortness of breath or uncontrolled pain (\> 3/10 on VAS) or pulse oxygen drops \< 92% or are unable to achieve the age-specified minimal ambulation distance.
  12. * Body weight more than 250 lbs.

Contacts and Locations

Study Contact

Shamali Dusane, MPT
CONTACT
3123552735
sdusan2@uic.edu
Lakshmi Kannan, MS PT
CONTACT
3124133175
lkanna2@uic.edu

Principal Investigator

Tanvi Bhatt, PhD
PRINCIPAL_INVESTIGATOR
University of Illinois at Chicago

Study Locations (Sites)

University of Illinois at Chicago
Chicago, Illinois, 60612
United States

Collaborators and Investigators

Sponsor: University of Illinois at Chicago

  • Tanvi Bhatt, PhD, PRINCIPAL_INVESTIGATOR, University of Illinois at Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-02-01
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2018-02-01
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Reactive balance
  • Virtual reality training
  • Surefooted platform

Additional Relevant MeSH Terms

  • Healthy Young
  • Healthy Aging
  • Stroke