RECRUITING

Effects of a Specific Substance in Smokers

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.

Official Title

An MRI Study of Neural Activity Following Exposure to a Specific Substance in Young Cigarette Smokers

Quick Facts

Study Start:2020-02-25
Study Completion:2024-03-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04281979

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participants must be 21-40 years old
  2. * Right-handed
  3. * Fluent in English
  4. * Report smoking cigarettes or e-cigarettes 1-27 days in the past month
  5. * Report binge drinking based on NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) at least 1 time in the past 90 days without adverse incident
  1. * Seeking treatment for substance use (e.g. nicotine or alcohol use)
  2. * Moderate or Severe Nicotine Dependence
  3. * Current alcohol use disorder
  4. * Illicit substance use other than marijuana use in the past year
  5. * Marijuana use more than 10 times in the past year
  6. * Major neurological or medical illness - Significant head trauma - Current use of medication affecting the central nervous system
  7. * MRI contraindications (e.g. irremovable metal on the body or pregnancy)

Contacts and Locations

Study Contact

Angelica M Morales, PhD
CONTACT
503-494-4221
moralean@ohsu.edu

Study Locations (Sites)

Oregon Health and Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-02-25
Study Completion Date2024-03-31

Study Record Updates

Study Start Date2020-02-25
Study Completion Date2024-03-31

Terms related to this study

Keywords Provided by Researchers

  • Nondaily Smoking
  • Craving
  • Impulsivity

Additional Relevant MeSH Terms

  • Smoking