Effects of a Specific Substance in Smokers

Description

Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.

Conditions

Smoking

Study Overview

Study Details

Study overview

Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.

An MRI Study of Neural Activity Following Exposure to a Specific Substance in Young Cigarette Smokers

Effects of a Specific Substance in Smokers

Condition
Smoking
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health and Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants must be 21-40 years old
  • * Right-handed
  • * Fluent in English
  • * Report smoking cigarettes or e-cigarettes 1-27 days in the past month
  • * Report binge drinking based on NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) at least 1 time in the past 90 days without adverse incident
  • * Seeking treatment for substance use (e.g. nicotine or alcohol use)
  • * Moderate or Severe Nicotine Dependence
  • * Current alcohol use disorder
  • * Illicit substance use other than marijuana use in the past year
  • * Marijuana use more than 10 times in the past year
  • * Major neurological or medical illness - Significant head trauma - Current use of medication affecting the central nervous system
  • * MRI contraindications (e.g. irremovable metal on the body or pregnancy)

Ages Eligible for Study

21 Years to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Oregon Health and Science University,

Study Record Dates

2024-03-31