RECRUITING

Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.

Official Title

Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

Quick Facts

Study Start:2020-02-25
Study Completion:2025-08-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04312269

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age at enrollment is 21 or older
  2. * Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
  3. * Severe to moderate motor impairment (FMA-UE of 7-40)
  4. * At least some voluntary shoulder and elbow muscle activation
  1. * Inability to follow instructions of the MyoCI task
  2. * Visual impairment (such as hemianopia) preventing full view of screen
  3. * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest)
  4. * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
  5. * Inability to understand or follow commands in English due to aphasia or other reason
  6. * Diffuse or multifocal infarcts in both hemispheres
  7. * Substantial arm pain preventing participation for 90 minutes a day
  8. * Spasticity treatment (pharmacological or Botox) within last 3 months
  9. * Ferromagnetic implants that are MRI incompatible

Contacts and Locations

Study Contact

Marc W Slutzky, MD/PhD
CONTACT
312-503-4653
mslutzky@northwestern.edu

Principal Investigator

Marc W Slutzky, MD/PhD
PRINCIPAL_INVESTIGATOR
Northwestern University

Study Locations (Sites)

Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Marc W Slutzky, MD/PhD, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-02-25
Study Completion Date2025-08-30

Study Record Updates

Study Start Date2020-02-25
Study Completion Date2025-08-30

Terms related to this study

Keywords Provided by Researchers

  • Sleep

Additional Relevant MeSH Terms

  • Stroke