RECRUITING

Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To compare two evidence-based treatments, Cognitive Enhancement Therapy (CET) and Social Skills Training (SST) that have been shown in meta-analyses and in our own research to be effective to improve community functioning. The investigators will test the impact of CET and SST on community functioning, with special attention to their relative effectiveness for patients differing in baseline cognitive skills and age. The research uses a cluster design in which different mental health service centers are randomized to one of the two treatments.

Official Title

Comparative Effectiveness of Cognitive Enhancement Therapy vs. Social Skills Training in Serious Mental Illness

Quick Facts

Study Start:2021-06-01
Study Completion:2026-01-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04321759

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. age 18 to 65;
  2. 2. DSM-5 diagnosis of schizophrenia or schizoaffective or schizophreniform disorder (confirmed via the MINI diagnostic interview);
  3. 3. estimated IQ of \> 70 (established via WTAR).
  1. 1. the presence of a current organic brain syndrome;
  2. 2. intellectual disability (DSM-5);
  3. 3. participation in either CET or SST within the prior year.

Contacts and Locations

Study Contact

Jennifer Sabbagh
CONTACT
617-975-8545
jsabbagh@bidmc.harvard.edu
Blanche Spindell
CONTACT
617-735-4261
bspindel@bidmc.harvard.edu

Principal Investigator

Matcheri S Keshavan, MD
PRINCIPAL_INVESTIGATOR
Beth Israel Deaconess Medical Center
Russell K Schutt, PhD
PRINCIPAL_INVESTIGATOR
Beth Israel Deaconess Medical Center

Study Locations (Sites)

Hartford Hospital - Institute of Living
Hartford, Connecticut, 06106
United States
Maine Medical Center
Portland, Maine, 04102
United States
Massachusetts Mental Health Center
Boston, Massachusetts, 02115
United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215
United States
UMass Medical School
Worcester, Massachusetts, 01603
United States

Collaborators and Investigators

Sponsor: Beth Israel Deaconess Medical Center

  • Matcheri S Keshavan, MD, PRINCIPAL_INVESTIGATOR, Beth Israel Deaconess Medical Center
  • Russell K Schutt, PhD, PRINCIPAL_INVESTIGATOR, Beth Israel Deaconess Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-06-01
Study Completion Date2026-01-31

Study Record Updates

Study Start Date2021-06-01
Study Completion Date2026-01-31

Terms related to this study

Keywords Provided by Researchers

  • Cognitive functioning
  • Social skills
  • Community functioning

Additional Relevant MeSH Terms

  • Schizophrenia and Related Disorders