COMPLETED

Biomechanical and Neural Mechanisms of Post-stroke Gait Training

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study seeks to develop an understanding of how, why, and for whom fast treadmill walking (Fast) and Fast with functional electrical stimulation (FastFES) induce clinical benefits, allowing future development of cutting-edge, individually-tailored gait treatments that enhance both gait quality and gait function.

Official Title

Biomechanical and Neural Mechanisms of Post-stroke Gait Training

Quick Facts

Study Start:2021-03-16
Study Completion:2025-10-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04380454

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:35 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * at least 6 months since stroke
  2. * single cortical or subcortical ischemic stroke
  3. * able to walk 10-meters with or without assistive device
  4. * sufficient cardiovascular health and ankle stability to walk on treadmill for 2-minutes at self-selected speed without orthosis
  5. * resting heart rate 40-100 bpm
  1. * hemorrhagic stroke
  2. * cerebellar signs (ataxic ("drunken") gait or decreased coordination during rapid alternating hand or foot movements
  3. * score of \>1 on question 1b and \>0 on question 1c on NIH Stroke Scale
  4. * inability to communicate with investigators
  5. * musculoskeletal conditions or pain that limit walking
  6. * neglect/hemianopia, or unexplained dizziness in last 6 months
  7. * neurologic conditions or diagnoses other than stroke
  8. * lack of sensation in lower limb affected by stroke
  9. * any medical diagnosis that would hinder the participant from completing the experimental trial
  10. * additional exclusion criteria due to contra-indications to TMS (measurement of corticospinal excitability) are: history of seizures, metal implants in the head or face, history of recurring or severe headaches/migraine, headache within the past 24 hours, presence of skull abnormalities or fractures, hemorrhagic stroke, history of dizziness, syncope, nausea, or loss of consciousness in the past 6 months

Contacts and Locations

Principal Investigator

Trisha Kesar, PT, PhD
PRINCIPAL_INVESTIGATOR
Emory University

Study Locations (Sites)

Emory University Hospital
Atlanta, Georgia, 30322
United States

Collaborators and Investigators

Sponsor: Emory University

  • Trisha Kesar, PT, PhD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-03-16
Study Completion Date2025-10-01

Study Record Updates

Study Start Date2021-03-16
Study Completion Date2025-10-01

Terms related to this study

Keywords Provided by Researchers

  • Rehabilitation
  • Post-stroke
  • Neural mechanism
  • Biomechanical mechanism
  • Electrical stimulation
  • Gait Training

Additional Relevant MeSH Terms

  • Stroke