COMPLETED

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Official Title

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Quick Facts

Study Start:2021-05-12
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04380610

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * SCA patients (HbSS and SB0 thalassemia)
  2. * Age: 5.0-50.0 at enrollment
  1. * Recent SCA complication associated with hospitalization (within 30 days) or ED visit (within 14 days)
  2. * Current AKI defined as \>0.3mg/g increase in SCr from prior visit
  3. * Known history of anaphylaxis with contrast agent or known pregnancy

Contacts and Locations

Principal Investigator

Jeffrey Lebensburger, DO, MSPH
PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham

Study Locations (Sites)

University of Alabama at Birmingham
Birmingham, Alabama, 35223
United States
University of Illinois Chicage
Chicago, Illinois, 60612
United States
St Jude Childrens Research Hospital
Memphis, Tennessee, 38106
United States
University of Tennessee Health Science Center
Memphis, Tennessee, 38163
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

  • Jeffrey Lebensburger, DO, MSPH, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-12
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2021-05-12
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Sickle Cell Disease
  • Renal Disease
  • Glomerular Disease