Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Description

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Conditions

Sickle Cell Disease, Renal Disease, Glomerular Disease

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Study Overview

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Study Details

Study overview

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Condition
Sickle Cell Disease
Intervention / Treatment

-

Contacts and Locations

Birmingham

University of Alabama at Birmingham, Birmingham, Alabama, United States, 35223

Chicago

University of Illinois Chicage, Chicago, Illinois, United States, 60612

Memphis

St Jude Childrens Research Hospital, Memphis, Tennessee, United States, 38106

Memphis

University of Tennessee Health Science Center, Memphis, Tennessee, United States, 38163

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * SCA patients (HbSS and SB0 thalassemia)
  • * Age: 5.0-50.0 at enrollment
  • * Recent SCA complication associated with hospitalization (within 30 days) or ED visit (within 14 days)
  • * Current AKI defined as \>0.3mg/g increase in SCr from prior visit
  • * Known history of anaphylaxis with contrast agent or known pregnancy

Ages Eligible for Study

5 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Alabama at Birmingham,

Jeffrey Lebensburger, DO, MSPH, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

2025-05-15