RECRUITING

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.

Official Title

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Quick Facts

Study Start:2019-10-01
Study Completion:2025-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04505618

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Both subjects with diseases and controls:
  2. * Children (age\<18)
  3. * Pregnant females
  4. * Developmentally delayed subjects
  5. * Subjects unable to provide informed consent
  6. * Inability to cooperate with tests and study instructions
  7. * Images with motion artifact or signal strength \< 7
  8. * History of glaucoma
  9. * History of age-related macular degeneration
  10. * History of any visually significant eye disease
  11. * History of proliferative diabetic retinopathy
  12. * History of any inflammatory disease
  13. * History of heart disease
  14. * History of thyroid disease.
  15. * Additional criteria for controls:
  16. * History of any type of Diabetes Mellitus
  17. * History of any type of Hypertension

Contacts and Locations

Study Contact

Amir H Kashani, MD, PhD
CONTACT
410-502-2789
akashan1@jhmi.edu
Ana C Martinez, MPH
CONTACT
410-502-2789
acollaz5@jhmi.edu

Principal Investigator

Amir Kashani, MD, MPH
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Wilmer Eye Institute
Baltimore, Maryland, 21287
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Amir Kashani, MD, MPH, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-10-01
Study Completion Date2025-09-01

Study Record Updates

Study Start Date2019-10-01
Study Completion Date2025-09-01

Terms related to this study

Additional Relevant MeSH Terms

  • Diabetic Retinopathy
  • Retinal Vein Occlusion
  • Hypertension,Essential
  • Retinal Vascular Disorder