Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Description

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.

Conditions

Diabetic Retinopathy, Retinal Vein Occlusion, Hypertension,Essential, Retinal Vascular Disorder

Study Overview

Study Details

Study overview

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

Condition
Diabetic Retinopathy
Intervention / Treatment

-

Contacts and Locations

Baltimore

Wilmer Eye Institute, Baltimore, Maryland, United States, 21287

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Both subjects with diseases and controls:
  • * Children (age\<18)
  • * Pregnant females
  • * Developmentally delayed subjects
  • * Subjects unable to provide informed consent
  • * Inability to cooperate with tests and study instructions
  • * Images with motion artifact or signal strength \< 7
  • * History of glaucoma
  • * History of age-related macular degeneration
  • * History of any visually significant eye disease
  • * History of proliferative diabetic retinopathy
  • * History of any inflammatory disease
  • * History of heart disease
  • * History of thyroid disease.
  • * Additional criteria for controls:
  • * History of any type of Diabetes Mellitus
  • * History of any type of Hypertension

Ages Eligible for Study

18 Years to 99 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Johns Hopkins University,

Amir Kashani, MD, MPH, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

2025-09-01