RECRUITING

tDCS and Cognitive Training for Mild Cognitive Impairment and Alzheimer's Dementia

Talk to us

Conditions

Alzheimer DiseaseMild Cognitive Impairment

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

There are currently no disease-modifying treatments for cognitive and behavioral symptoms associated with early clinical Alzheimer's disease (AD), and only minimally effective symptomatic treatments are available. In this application, we propose a transcranial direct current stimulation (tDCS) augmented executive functioning training intervention. This intervention will target cognition and brain circuits that are impaired in patients with mild cognitive impairment (MCI) and early AD. The goal is to improve cognitive performance and functional outcomes in patients with MCI and early AD.

Official Title

Combined tDCS and Cognitive Training for Mild Cognitive Impairment (MCI) and Early Clinical Alzheimer's Type Dementia (CATD)

Quick Facts

Study Start:2020-09-24
Study Completion:2024-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04507815

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * are a Veteran receiving services from the MVAHCS GRECC clinic
  2. * have a clinical diagnosis of AD, MCI, or Mild Neurocognitive Disorder presenting as early AD type (predominantly amnestic and dysexecutive)
  3. * are age 60 or older
  4. * are stable on any medications for at least 1 month at the baseline visit
  5. * demonstrate capacity to provide informed consent
  6. * have WiFi access in their home
  7. * have a family member or friend willing to serve as a care partner (care partner needs to have a minimum of 10 hours per week that they see the participant, if they don't live with them).
  1. * any significant medical disorder based on the Principal Investigator's judgment that would impact risk
  2. * other psychiatric or neurological conditions that impact cognition
  3. * metallic cranial plates/screws or implanted devices above the clavicle
  4. * eczema on scalp or other scalp lesions or skin disorders that may become irritated by stimulation

Contacts and Locations

Study Contact

John R McCarten, MD
CONTACT
612-467-3314
Riley.McCarten@va.gov

Principal Investigator

John R McCarten, MD
PRINCIPAL_INVESTIGATOR
Minneapolis Veterans Affairs Medical Center

Study Locations (Sites)

Minneapolis VA Health Care System
Minneapolis, Minnesota, 55417
United States

Collaborators and Investigators

Sponsor: Minneapolis Veterans Affairs Medical Center

  • John R McCarten, MD, PRINCIPAL_INVESTIGATOR, Minneapolis Veterans Affairs Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-09-24
Study Completion Date2024-09

Study Record Updates

Study Start Date2020-09-24
Study Completion Date2024-09

Terms related to this study

Additional Relevant MeSH Terms

  • Alzheimer Disease
  • Mild Cognitive Impairment