RECRUITING

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is being done to determine if patients receiving personalized exercise therapy (versus those who do not receive personalized exercise therapy) have improved quality of life and physical functioning after completing their radiation therapy. Second, the study is being done to find if the quality of life changes during therapy correlate with measurements of inflammation in the blood. Third, the study is being done to see if adding exercise therapy to radiation therapy will improve survival.

Official Title

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

Quick Facts

Study Start:2023-12-11
Study Completion:2026-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04556045

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subjects must have metastatic disease consistent with prostate cancer
  2. * Males ≥18 years of age receiving first palliative course of RT for metastatic prostate cancer
  3. * Patient receiving radiation dose of 20 Gray (Gy) in 5 fractions or stereotactic body radiation therapy (SBRT)
  4. * Patient may have received prior hormone therapy. Prior or current use of chemotherapy agents is allowed, but not necessary.
  5. * Fluent in written and spoken English
  6. * Must be able to provide and understand informed consent
  7. * Must have an ECOG Performance Status (PS) of ≤ 3
  8. * Primary attending radiation oncologist approval
  1. * Performing \> 90 minutes/week of exercise therapy prior at time of enrollment
  2. * Evidence in the medical record of an absolute contraindication for exercise
  3. * Cardiac

Contacts and Locations

Study Contact

Nicholas G Zaorsky, MD, MS
CONTACT
1-800-641-2422
Nicholas.Zaorsky@uhhospitals.org

Principal Investigator

Nicholas Zaorsky, MD
PRINCIPAL_INVESTIGATOR
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Study Locations (Sites)

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106
United States

Collaborators and Investigators

Sponsor: Case Comprehensive Cancer Center

  • Nicholas Zaorsky, MD, PRINCIPAL_INVESTIGATOR, University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-12-11
Study Completion Date2026-01-01

Study Record Updates

Study Start Date2023-12-11
Study Completion Date2026-01-01

Terms related to this study

Keywords Provided by Researchers

  • Exercise
  • Radiation
  • Prostate Cancer

Additional Relevant MeSH Terms

  • Metastatic Prostate Cancer