RECRUITING

CHronic Nonbacterial Osteomyelitis International Registry

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.

Official Title

CHronic Nonbacterial Osteomyelitis International Registry (CHOIR)

Quick Facts

Study Start:2018-08-01
Study Completion:2050-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04725422

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * - Age at enrollment is equal to or younger than 21 years of age
  2. * Presence of bone edema on STIR or T2 fat saturation sequence on MRI within 12 weeks of enrollment
  3. * Whole body imaging evaluation (either WB MRI or bone scintigraphy)
  4. * Bone biopsy to exclude infection or malignancy unless bone lesions follow typical distribution or there is IBD, psoriasis, or palmar plantar pustulosis
  1. * - History of or current malignancy
  2. * Current infectious osteomyelitis
  3. * Contraindication to the selected treatment agent

Contacts and Locations

Study Contact

Yongdong (Dan) Zhao, MD, PhD
CONTACT
206-987-2000
crmoresearch@seattlechildrens.org

Study Locations (Sites)

Seattle Children's Hospital
Seattle, Washington, 98105
United States

Collaborators and Investigators

Sponsor: Seattle Children's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-08-01
Study Completion Date2050-08

Study Record Updates

Study Start Date2018-08-01
Study Completion Date2050-08

Terms related to this study

Additional Relevant MeSH Terms

  • Chronic Nonbacterial Osteomyelitis
  • Chronic Recurrent Multifocal Osteomyelitis