CHronic Nonbacterial Osteomyelitis International Registry

Description

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.

Conditions

Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis

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Study Overview

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Study Details

Study overview

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.

CHronic Nonbacterial Osteomyelitis International Registry (CHOIR)

CHronic Nonbacterial Osteomyelitis International Registry

Condition
Chronic Nonbacterial Osteomyelitis
Intervention / Treatment

-

Contacts and Locations

Seattle

Seattle Children's Hospital, Seattle, Washington, United States, 98105

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * - Age at enrollment is equal to or younger than 21 years of age
  • * Presence of bone edema on STIR or T2 fat saturation sequence on MRI within 12 weeks of enrollment
  • * Whole body imaging evaluation (either WB MRI or bone scintigraphy)
  • * Bone biopsy to exclude infection or malignancy unless bone lesions follow typical distribution or there is IBD, psoriasis, or palmar plantar pustulosis
  • * - History of or current malignancy
  • * Current infectious osteomyelitis
  • * Contraindication to the selected treatment agent

Ages Eligible for Study

to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Seattle Children's Hospital,

Study Record Dates

2050-08