COMPLETED

Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery.

Official Title

Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery

Quick Facts

Study Start:2021-11-16
Study Completion:2025-10-20
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04791943

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subject must have 3-4 partial or full bony impacted third molars requiring surgical extraction under IV sedation
  2. * Ages 18-35
  3. * American Society of Anesthesiologists (ASA) Class I or II
  4. * English or Spanish speaking patients
  5. * Capacity to sign informed consent
  1. * Allergies to melatonin, opioids, or other Over-the-counter (OTC) pain medications
  2. * Anyone currently taking melatonin for any reason
  3. * Cases under local anesthesia
  4. * ASA class III or higher
  5. * Sleep disorder (insomnia/narcolepsy)
  6. * Current or past history of substance abuse
  7. * Chronic pain
  8. * Language/communication barrier
  9. * Psychiatric disease/ Mental impairment
  10. * Current or past use of psychotropic drugs
  11. * Pregnancy
  12. * Renal or hepatic impairment
  13. * BMI \>35

Contacts and Locations

Principal Investigator

Jason Baker, DMD
PRINCIPAL_INVESTIGATOR
Montefiore Medical Center

Study Locations (Sites)

Montefiore Medical Center Department of Dentistry
The Bronx, New York, 10467
United States

Collaborators and Investigators

Sponsor: Montefiore Medical Center

  • Jason Baker, DMD, PRINCIPAL_INVESTIGATOR, Montefiore Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-11-16
Study Completion Date2025-10-20

Study Record Updates

Study Start Date2021-11-16
Study Completion Date2025-10-20

Terms related to this study

Additional Relevant MeSH Terms

  • Pain, Postoperative
  • Narcotic Use