RECRUITING

Autologous Mitochondrial Transplant for Cerebral Ischemia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

Official Title

Study Title: Autologous Mitochondrial Transplant for Cerebral Ischemia

Quick Facts

Study Start:2021-04-29
Study Completion:2026-10-29
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04998357

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Eligible for endovascular thrombectomy to treat acute large vessel occlusion
  2. * Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage
  3. * Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative
  1. * Unable to receive a brain MRI scan
  2. * Known mitochondrial disease
  3. * Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed

Contacts and Locations

Study Contact

Study Coordinator
CONTACT
206-897-5802
sanslab@uw.edu

Principal Investigator

Melanie S Walker, MD
PRINCIPAL_INVESTIGATOR
University of Washington

Study Locations (Sites)

Harborview Medical Center
Seattle, Washington, 98104
United States

Collaborators and Investigators

Sponsor: University of Washington

  • Melanie S Walker, MD, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-04-29
Study Completion Date2026-10-29

Study Record Updates

Study Start Date2021-04-29
Study Completion Date2026-10-29

Terms related to this study

Keywords Provided by Researchers

  • autologous mitochondrial transplantation
  • ischemic stroke

Additional Relevant MeSH Terms

  • Cerebral Ischemia