Autologous Mitochondrial Transplant for Cerebral Ischemia

Description

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

Conditions

Cerebral Ischemia

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Study Overview

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Study Details

Study overview

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

Study Title: Autologous Mitochondrial Transplant for Cerebral Ischemia

Autologous Mitochondrial Transplant for Cerebral Ischemia

Condition
Cerebral Ischemia
Intervention / Treatment

-

Contacts and Locations

Seattle

Harborview Medical Center, Seattle, Washington, United States, 98104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Eligible for endovascular thrombectomy to treat acute large vessel occlusion
  • * Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage
  • * Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative
  • * Unable to receive a brain MRI scan
  • * Known mitochondrial disease
  • * Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Washington,

Melanie S Walker, MD, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

2026-10-29