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Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Description

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Conditions

Traumatic Brain Injury
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Related Conditions:

Traumatic Brain Injury

Study Overview

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Study Details

Study overview

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury (RAPID-TBI)

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Condition
Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Baltimore

University of Maryland Medical Center, Baltimore, Maryland, United States, 21210

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Arrival to the hospital within 6 hours of injury
  • * Age \>= 18 years old
  • * Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings.
  • * Deemed to have a non-survivable TBI
  • * Brain dead on arrival
  • * Active substance abuse for opiates and cocaine as noted by admission toxicology screen.
  • * Any thoracic or abdominal injury resulting in open surgical intervention
  • * Pregnancy
  • * Prisoners
  • * Active military
  • * Non - English speaking (due to necessity for consent in aims 2 and 3)
  • * Age \> 89 years

Ages Eligible for Study

18 Years to 79 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Maryland, Baltimore,

Study Record Dates

2026-10-31