Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Description

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Conditions

Traumatic Brain Injury

Study Overview

Study Details

Study overview

This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury (RAPID-TBI)

Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Condition
Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Baltimore

University of Maryland Medical Center, Baltimore, Maryland, United States, 21210

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Arrival to the hospital within 6 hours of injury
  • * Age \>= 18 years old
  • * Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings.
  • * Deemed to have a non-survivable TBI
  • * Brain dead on arrival
  • * Active substance abuse for opiates and cocaine as noted by admission toxicology screen.
  • * Any thoracic or abdominal injury resulting in open surgical intervention
  • * Pregnancy
  • * Prisoners
  • * Active military
  • * Non - English speaking (due to necessity for consent in aims 2 and 3)
  • * Age \> 89 years

Ages Eligible for Study

18 Years to 79 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Maryland, Baltimore,

Study Record Dates

2026-10-31