RECRUITING

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal mice by impairing skeletal muscle mitochondrial function and fat oxidation. However, relevance of this findings in humans remains unknown.

Official Title

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

Quick Facts

Study Start:2022-09-14
Study Completion:2028-03-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05147909

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. 1. history of cardiopulmonary disease or chronic kidney disease,
  2. 2. treatment with antihypertensive medications,
  3. 3. estimated glomerular filtration rate (eGFR) \< 60 mL/min/1.73m2, (4) diabetes mellitus or other systemic illness,

Contacts and Locations

Study Contact

John Giacona, PA-C
CONTACT
2146484403
john.giacona@utsouthwestern.edu

Principal Investigator

Wanpen Vongpatanasin, MD
PRINCIPAL_INVESTIGATOR
Wanpen.Vongpatanasin@UTSouthwestern.edu

Study Locations (Sites)

University of Texas Southwestern
Dallas, Texas, 75209
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

  • Wanpen Vongpatanasin, MD, PRINCIPAL_INVESTIGATOR, Wanpen.Vongpatanasin@UTSouthwestern.edu

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-14
Study Completion Date2028-03-30

Study Record Updates

Study Start Date2022-09-14
Study Completion Date2028-03-30

Terms related to this study

Additional Relevant MeSH Terms

  • Physical Inactivity
  • Phosphate Overload
  • Visceral Obesity