RECRUITING

Neurostimulation for the Treatment of Post-Stroke Aphasia

Description

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

Conditions

Post-stroke Aphasia
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Related Conditions:

Post-stroke Aphasia

Study Overview

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Study Details

Study overview

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

Neurostimulation for the Treatment of Post-Stroke Aphasia

Neurostimulation for the Treatment of Post-Stroke Aphasia

Condition
Post-stroke Aphasia
Intervention / Treatment

-

Contacts and Locations

New York

Abilities Research Center at Mount Sinai, New York, New York, United States, 10029

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * diagnosis of aphasia: Broca's or mixed (based on the assessment of a Speech Language Pathologist).
  • * presence of a focus of injury in the left hemisphere (within one hemisphere only) as a result of the first ischemic or hemorrhagic stroke (based on CT/MRI examination);
  • * chronic stage of the disease - time since the stroke occurred over 6 months.
  • * ability to achieve an accuracy in the Naming Task of 10-60%.
  • * 18-80 years
  • * right-handedness before the stroke.
  • * ability to give informed written consent.
  • * fluency in English.
  • * severe cognitive, auditory or visual impairment that would preclude cognitive and language testing - inability to follow a two-step command.
  • * presence of metal implants in the skull.
  • * presence of major untreated or unstable psychiatric disease.
  • * history of epilepsy or seizures.
  • * ongoing medication that increases the risk of epileptic seizures.
  • * presence in the body of cardiac stimulators or pacemaker.
  • * history of speech, language, hearing, or intellectual disability during childhood.
  • * pregnancy (based on declarations)
  • * high intolerance to stimulation.
  • * occurrence of an epileptic seizure.
  • * other previously absent neurological or mental symptoms
  • * high intolerance to stimulation (participants experience severe discomfort during stimulation);
  • * occurrence of an epileptic seizure;
  • * other previously absent neurological, physical or mental symptoms.

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Neuro Device S.A,

Miguel Escalon, MD, MPH, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

2025-06