RECRUITING

Neurostimulation for the Treatment of Post-Stroke Aphasia

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Conditions

Post-stroke Aphasiaspeech therapybrain stimulationcommunicationlanguage

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.

Official Title

Neurostimulation for the Treatment of Post-Stroke Aphasia

Quick Facts

Study Start:2023-09-06
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05194566

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * diagnosis of aphasia: Broca's or mixed (based on the assessment of a Speech Language Pathologist).
  2. * presence of a focus of injury in the left hemisphere (within one hemisphere only) as a result of the first ischemic or hemorrhagic stroke (based on CT/MRI examination);
  3. * chronic stage of the disease - time since the stroke occurred over 6 months.
  4. * ability to achieve an accuracy in the Naming Task of 10-60%.
  5. * 18-80 years
  6. * right-handedness before the stroke.
  7. * ability to give informed written consent.
  8. * fluency in English.
  1. * severe cognitive, auditory or visual impairment that would preclude cognitive and language testing - inability to follow a two-step command.
  2. * presence of metal implants in the skull.
  3. * presence of major untreated or unstable psychiatric disease.
  4. * history of epilepsy or seizures.
  5. * ongoing medication that increases the risk of epileptic seizures.
  6. * presence in the body of cardiac stimulators or pacemaker.
  7. * history of speech, language, hearing, or intellectual disability during childhood.
  8. * pregnancy (based on declarations)
  9. * high intolerance to stimulation.
  10. * occurrence of an epileptic seizure.
  11. * other previously absent neurological or mental symptoms
  12. * high intolerance to stimulation (participants experience severe discomfort during stimulation);
  13. * occurrence of an epileptic seizure;
  14. * other previously absent neurological, physical or mental symptoms.

Contacts and Locations

Study Contact

Courtney McSweeney
CONTACT
(929) 237-3930
Courtney.McSweeney@mountsinai.org
Aidan Rogers
CONTACT
(718) 308-9450
aidan.rogers@mountsinai.org

Principal Investigator

Miguel Escalon, MD, MPH
PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai

Study Locations (Sites)

Abilities Research Center at Mount Sinai
New York, New York, 10029
United States

Collaborators and Investigators

Sponsor: Neuro Device S.A

  • Miguel Escalon, MD, MPH, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-06
Study Completion Date2025-06

Study Record Updates

Study Start Date2023-09-06
Study Completion Date2025-06

Terms related to this study

Keywords Provided by Researchers

  • speech therapy
  • brain stimulation
  • communication
  • language

Additional Relevant MeSH Terms

  • Post-stroke Aphasia