RECRUITING

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Description

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" intervention designed to lower insulin resistance through healthy food access, food utilization skills, and other self-care behaviors. Knowledge gained from this study can benefit those living with HIV through the prevention and more effective management of pre-diabetes, diabetes, obesity, and non-alcoholic fatty liver disease.

Study Overview

Study Details

Study overview

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" intervention designed to lower insulin resistance through healthy food access, food utilization skills, and other self-care behaviors. Knowledge gained from this study can benefit those living with HIV through the prevention and more effective management of pre-diabetes, diabetes, obesity, and non-alcoholic fatty liver disease.

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Condition
HIV
Intervention / Treatment

-

Contacts and Locations

Tulsa

OU Integrative Immunology Center, Tulsa, Oklahoma, United States, 74135

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * HIV-positive with income \<400% federal poverty level
  • * at least 1 risk factor for insulin resistance per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (i.e., overweight/obesity, age 45 yrs or older, immediate family member with diabetes, non-white race, physical inactivity, history of gestational diabetes, history of heart disease or stroke, diagnosis of polycystic ovarian syndrome, high blood pressure, high cholesterol, or hepatitis C virus antibody positivity
  • * using antiretroviral therapy for at least 6 months
  • * English-speaking
  • * participating in another health-related research study
  • * receiving treatment for a terminal or other serious illness, such as cancer or end-stage renal failure
  • * plan to move outside of Oklahoma during the study period
  • * does not have an address that can accept home-delivered groceries

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Oklahoma,

Marianna S Wetherill, PhD, MPH, RD, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

2025-12