RECRUITING

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" intervention designed to lower insulin resistance through healthy food access, food utilization skills, and other self-care behaviors. Knowledge gained from this study can benefit those living with HIV through the prevention and more effective management of pre-diabetes, diabetes, obesity, and non-alcoholic fatty liver disease.

Official Title

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

Quick Facts

Study Start:2020-10-09
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05208671

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * HIV-positive with income \<400% federal poverty level
  2. * at least 1 risk factor for insulin resistance per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (i.e., overweight/obesity, age 45 yrs or older, immediate family member with diabetes, non-white race, physical inactivity, history of gestational diabetes, history of heart disease or stroke, diagnosis of polycystic ovarian syndrome, high blood pressure, high cholesterol, or hepatitis C virus antibody positivity
  3. * using antiretroviral therapy for at least 6 months
  4. * English-speaking
  1. * participating in another health-related research study
  2. * receiving treatment for a terminal or other serious illness, such as cancer or end-stage renal failure
  3. * plan to move outside of Oklahoma during the study period
  4. * does not have an address that can accept home-delivered groceries

Contacts and Locations

Study Contact

Lacey Caywood, MPH
CONTACT
918-834-4194
nourish@tulsacares.org

Principal Investigator

Marianna S Wetherill, PhD, MPH, RD
PRINCIPAL_INVESTIGATOR
University of Oklahoma

Study Locations (Sites)

OU Integrative Immunology Center
Tulsa, Oklahoma, 74135
United States

Collaborators and Investigators

Sponsor: University of Oklahoma

  • Marianna S Wetherill, PhD, MPH, RD, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-10-09
Study Completion Date2025-12

Study Record Updates

Study Start Date2020-10-09
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • food as medicine
  • nutrition

Additional Relevant MeSH Terms

  • HIV
  • Insulin Resistance
  • Food Insecurity