RECRUITING

Engage for Late-Life Depression and Comorbid Executive Dysfunction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is a behavioral treatment approach that has shown to be effective in treating late life depression. The investigators are testing the feasibility of Engage as a treatment method for late life depression in older adults with cognitive decline. The objective is to corroborate Engage as an alternative late life depression treatment method for a sub-population of older adults with cognitive decline. Cognitive decline poses a unique mental health treatment barrier that is often over looked in younger populations. With a relatively higher prevalence of cognitive decline in older adulthood, it is imperative that a feasible mental health treatment program that can be effective in the presence of cognitive decline.

Official Title

Engage: A Treatment for Late-Life Depression and Comorbid Executive/Cognitive Dysfunction

Quick Facts

Study Start:2023-09-24
Study Completion:2025-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05356611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 60 or older
  2. * Ability to read, write, and speak English
  3. * Located in Las Vegas or surrounding area
  4. * Ability to travel to UNLV campus by self or possible caregiver for regular study visits
  5. * Clinically significant symptoms of depression as evidenced by: 1) Scores \> 5 on the Geriatric Depression Scale-Short Form (GDS-SF)
  6. * Mild cognitive impairment as evidenced by: 1) Scores \> 18 and \< 25 on the Montreal Cognitive Assessment (MoCA)
  1. * Active suicidal ideation
  2. * History of suicide attempt(s)
  3. * Current symptoms of: 1) Psychosis; 2) Active substance use disorder
  4. * Reported history of: 1) Bipolar disorder ("manic depression"); 2) Intellectual disability
  5. * Currently in or scheduled to initiate individual psychotherapy to avoid treatment interference
  6. * Psychotropic medication permitted if dose was stable over the past 2 weeks
  7. * Currently living in an institutional setting (e.g., assisted living, inpatient, skilled nursing)
  8. * Presence of notable memory-specific cognitive deficits as evidenced by: scores \< 9 on the MoCA memory subscale (rendering it difficult to participate in and track/recall events for weekly psychotherapy)

Contacts and Locations

Study Contact

Brenna R Renn, PhD
CONTACT
7028950596
brenna.renn@unlv.edu
Matthew S Schurr, MA
CONTACT
7026957708
schurm1@unlv.nevada.edu

Study Locations (Sites)

University of Nevada
Las Vegas, Nevada, 89154
United States

Collaborators and Investigators

Sponsor: University of Nevada, Las Vegas

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-24
Study Completion Date2025-05

Study Record Updates

Study Start Date2023-09-24
Study Completion Date2025-05

Terms related to this study

Keywords Provided by Researchers

  • Older Adults
  • Late-Life Depression

Additional Relevant MeSH Terms

  • Depression in Old Age
  • Psychotherapy
  • Mild Cognitive Impairment
  • Executive Dysfunction