Engage for Late-Life Depression and Comorbid Executive Dysfunction

Description

Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is a behavioral treatment approach that has shown to be effective in treating late life depression. The investigators are testing the feasibility of Engage as a treatment method for late life depression in older adults with cognitive decline. The objective is to corroborate Engage as an alternative late life depression treatment method for a sub-population of older adults with cognitive decline. Cognitive decline poses a unique mental health treatment barrier that is often over looked in younger populations. With a relatively higher prevalence of cognitive decline in older adulthood, it is imperative that a feasible mental health treatment program that can be effective in the presence of cognitive decline.

Conditions

Depression in Old Age, Psychotherapy, Mild Cognitive Impairment, Executive Dysfunction

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Study Overview

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Study Details

Study overview

Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is a behavioral treatment approach that has shown to be effective in treating late life depression. The investigators are testing the feasibility of Engage as a treatment method for late life depression in older adults with cognitive decline. The objective is to corroborate Engage as an alternative late life depression treatment method for a sub-population of older adults with cognitive decline. Cognitive decline poses a unique mental health treatment barrier that is often over looked in younger populations. With a relatively higher prevalence of cognitive decline in older adulthood, it is imperative that a feasible mental health treatment program that can be effective in the presence of cognitive decline.

Engage: A Treatment for Late-Life Depression and Comorbid Executive/Cognitive Dysfunction

Engage for Late-Life Depression and Comorbid Executive Dysfunction

Condition
Depression in Old Age
Intervention / Treatment

-

Contacts and Locations

Las Vegas

University of Nevada, Las Vegas, Nevada, United States, 89154

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 60 or older
  • * Ability to read, write, and speak English
  • * Located in Las Vegas or surrounding area
  • * Ability to travel to UNLV campus by self or possible caregiver for regular study visits
  • * Clinically significant symptoms of depression as evidenced by: 1) Scores \> 5 on the Geriatric Depression Scale-Short Form (GDS-SF)
  • * Mild cognitive impairment as evidenced by: 1) Scores \> 18 and \< 25 on the Montreal Cognitive Assessment (MoCA)
  • * Active suicidal ideation
  • * History of suicide attempt(s)
  • * Current symptoms of: 1) Psychosis; 2) Active substance use disorder
  • * Reported history of: 1) Bipolar disorder ("manic depression"); 2) Intellectual disability
  • * Currently in or scheduled to initiate individual psychotherapy to avoid treatment interference
  • * Psychotropic medication permitted if dose was stable over the past 2 weeks
  • * Currently living in an institutional setting (e.g., assisted living, inpatient, skilled nursing)
  • * Presence of notable memory-specific cognitive deficits as evidenced by: scores \< 9 on the MoCA memory subscale (rendering it difficult to participate in and track/recall events for weekly psychotherapy)

Ages Eligible for Study

60 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Nevada, Las Vegas,

Study Record Dates

2025-05