RECRUITING

PV Loop & Coarctation Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.

Official Title

Assessment of the Impact of Transcatheter Stenting of Aortic Coarctation on the Left Ventricular Afterload and Work Using Left Ventricular Pressure Volume Loops

Quick Facts

Study Start:2019-06-04
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05362721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:6 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Children 6 years of age and older and adults of all races and both sexes referred for elective cardiac catheterization and stent therapy for coarctation
  2. * Those who provide informed consent for study participant.
  1. * Children who undergo other interventions in addition to the coarctation
  2. * Children with single ventricle physiology.
  3. * Renal impairment
  4. * Participant unwilling to sign a consent form.

Contacts and Locations

Study Contact

Brittany Faanes
CONTACT
612-625-5929
grego318@umn.edu

Principal Investigator

Gurumurthy Hiremath
PRINCIPAL_INVESTIGATOR
University of Minnesota

Study Locations (Sites)

Children's Hospital of Los Angeles
Los Angeles, California, 90027
United States
Children's Hospital of Boston
Boston, Massachusetts, 02115
United States
Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503
United States
University of Minnesota
Minneapolis, Minnesota, 55455
United States
Children's Mercy Hospital
Kansas City, Missouri, 64108
United States
Cincinnati Children's Hospital
Cincinnati, Ohio, 45229
United States
University of Texas-Southwestern
Dallas, Texas, 75390
United States

Collaborators and Investigators

Sponsor: University of Minnesota

  • Gurumurthy Hiremath, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-06-04
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2019-06-04
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • Coarctation of Aorta
  • COA

Additional Relevant MeSH Terms

  • Coarctation of Aorta