RECRUITING

Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

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Conditions

Mediastinal LymphadenopathySarcoidosis, PulmonaryMediastinal DiseasesSarcoidosisBronchoscopyEndobronchial UltrasoundIntranodal forceps biopsy

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.

Official Title

Evaluating the Diagnostic Yield and Specimen Quality With Endobronchial Ultrasound-Guided Intranodal Forceps Biopsies in Patients With Mediastinal and Hilar Lymphadenopathy: A Prospective Analysis

Quick Facts

Study Start:2022-06-10
Study Completion:2025-03-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05374447

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Radiologic evidence of mediastinal and/or hilar lymphadenopathy
  2. * Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
  3. * Age 18 years or older
  4. * Severe pulmonary hypertension
  5. * Inability to undergo general anesthesia
  6. * Severe coagulopathy or bleeding diathesis
  7. * Previously diagnosed sarcoidosis
  8. * Patient presently taking clopidogrel
  9. * Patient deemed to be high risk for general anesthesia per anesthesiologist
  10. * Hemodynamic instability
  11. * Mediastinitis
  12. * Acute Hypercarbic Respiratory Failure (pCO2 \>55mmHg)
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Khalil Diab, MD
CONTACT
2027412180
kdiab@mfa.gwu.edu
Benjamin Delprete, DO
CONTACT
2027412180
bdelprete@mfa.gwu.edu

Principal Investigator

Mardi Gomberg, MD
STUDY_DIRECTOR
The George Washington University

Study Locations (Sites)

The George Washington University Hospital
Washington, District of Columbia, 20037
United States

Collaborators and Investigators

Sponsor: George Washington University

  • Mardi Gomberg, MD, STUDY_DIRECTOR, The George Washington University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-10
Study Completion Date2025-03-01

Study Record Updates

Study Start Date2022-06-10
Study Completion Date2025-03-01

Terms related to this study

Keywords Provided by Researchers

  • Sarcoidosis
  • Bronchoscopy
  • Endobronchial Ultrasound
  • Intranodal forceps biopsy

Additional Relevant MeSH Terms

  • Mediastinal Lymphadenopathy
  • Sarcoidosis, Pulmonary
  • Mediastinal Diseases