Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

Description

The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.

Conditions

Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary, Mediastinal Diseases

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Study Overview

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Study Details

Study overview

The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.

Evaluating the Diagnostic Yield and Specimen Quality With Endobronchial Ultrasound-Guided Intranodal Forceps Biopsies in Patients With Mediastinal and Hilar Lymphadenopathy: A Prospective Analysis

Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

Condition
Mediastinal Lymphadenopathy
Intervention / Treatment

-

Contacts and Locations

Washington

The George Washington University Hospital, Washington, District of Columbia, United States, 20037

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Radiologic evidence of mediastinal and/or hilar lymphadenopathy
  • * Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
  • * Age 18 years or older
  • * Severe pulmonary hypertension
  • * Inability to undergo general anesthesia
  • * Severe coagulopathy or bleeding diathesis
  • * Previously diagnosed sarcoidosis
  • * Patient presently taking clopidogrel
  • * Patient deemed to be high risk for general anesthesia per anesthesiologist
  • * Hemodynamic instability
  • * Mediastinitis
  • * Acute Hypercarbic Respiratory Failure (pCO2 \>55mmHg)

Ages Eligible for Study

18 Years to 99 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

George Washington University,

Mardi Gomberg, MD, STUDY_DIRECTOR, The George Washington University

Study Record Dates

2025-03-01