RECRUITING

Botulinum Toxin Therapy in Hidradenitis Suppurativa

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease Hidradenitis Suppurativa (HS). In this study, the investigators will test the hypothesis that inhibiting neuropeptide activity with botulinum toxin reduces pathogenic inflammation.

Official Title

Targeting Nociceptors in Hidradenitis Suppurativa

Quick Facts

Study Start:2022-06-07
Study Completion:2028-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05403710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Sarah K Whitley, MD PhD
CONTACT
(508)334-5979
sarah.whitley@umassmed.edu
Michelle Landry, MPH
CONTACT
(508)856-6621
michelle.landry@umassmed.edu

Principal Investigator

Sarah K Whitley, MD PhD
PRINCIPAL_INVESTIGATOR
Assistant Professor of Dermatology

Study Locations (Sites)

University of Massachusetts Chan Medical School
Worcester, Massachusetts, 01605
United States

Collaborators and Investigators

Sponsor: University of Massachusetts, Worcester

  • Sarah K Whitley, MD PhD, PRINCIPAL_INVESTIGATOR, Assistant Professor of Dermatology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-07
Study Completion Date2028-04-30

Study Record Updates

Study Start Date2022-06-07
Study Completion Date2028-04-30

Terms related to this study

Additional Relevant MeSH Terms

  • Hidradenitis Suppurativa
  • Hyperhidrosis