RECRUITING

Modulating Exercise Dosage to Improve Concussion Recovery

Description

Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects, how exercise can alter concussion-related pathophysiology, and whether exercise can prevent the development of secondary sequelae. Our objective is to examine if a high dose exercise program (higher volume than currently prescribed at an individualized, safe intensity level) initiated within 14 days of concussion results in faster symptom resolution, altered physiological function, or reduced secondary sequalae. Findings from this research will lead to more rigorous and precise rehabilitation guidelines and improved understanding about how exercise affects neurophysiological function among adolescents with concussion.

Study Overview

Study Details

Study overview

Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects, how exercise can alter concussion-related pathophysiology, and whether exercise can prevent the development of secondary sequelae. Our objective is to examine if a high dose exercise program (higher volume than currently prescribed at an individualized, safe intensity level) initiated within 14 days of concussion results in faster symptom resolution, altered physiological function, or reduced secondary sequalae. Findings from this research will lead to more rigorous and precise rehabilitation guidelines and improved understanding about how exercise affects neurophysiological function among adolescents with concussion.

Modulating Exercise Dosage to Improve Concussion Recovery: a Randomized Clinical Trial

Modulating Exercise Dosage to Improve Concussion Recovery

Condition
Concussion, Brain
Intervention / Treatment

-

Contacts and Locations

Aurora

University of Colorado Denver, Aurora, Colorado, United States, 80045

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Cambridge

Spaulding Rehabilitation Hospital, Cambridge, Massachusetts, United States, 02138

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 13-18 years of age
  • * Post-Concussion Symptom Scale (PCSS) score \>10 to ensure participants are not recovered by enrollment
  • * Concussion diagnosis by a sports medicine physician
  • * Pre-existing neurological disorders
  • * Exercise contraindications
  • * Concussion \<6 months before enrollment (excluding the current injury)

Ages Eligible for Study

13 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Colorado, Denver,

David R Howell, PhD, PRINCIPAL_INVESTIGATOR, University of Colorado Denver | Anschutz

Study Record Dates

2027-02-01