RECRUITING

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by application of auditory and electrical stimulations during sleep and its effect on modulating memory processes.

Official Title

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Quick Facts

Study Start:2022-07-13
Study Completion:2026-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05452122

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All epilepsy patients between the ages of 18 and 65 who undergo depth electrode placement for clinical purposes
  2. * Eligibility is determined by the epilepsy surgery team (based on neuropsychological testing and on psychiatric evaluation)
  3. * Willing to provide informed consent and participate the study
  1. * Neurological or psychiatric issues, other than epilepsy, that would put the patient at risk
  2. * Patient is younger than 18 or older than 65 years of age
  3. * Unwilling to provide informed consent

Contacts and Locations

Study Contact

Andreina Hampton
CONTACT
3236105293
amhampton@mednet.ucla.edu

Study Locations (Sites)

University of California Los Angeles
Los Angeles, California, 90095
United States

Collaborators and Investigators

Sponsor: University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-07-13
Study Completion Date2026-08-31

Study Record Updates

Study Start Date2022-07-13
Study Completion Date2026-08-31

Terms related to this study

Keywords Provided by Researchers

  • sleep
  • stimulation
  • memory
  • learning
  • single-unit

Additional Relevant MeSH Terms

  • Memory, Delayed