RECRUITING

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

Official Title

Acute and Chronic Impacts of Muscadine Wine Polyphenols on Cognition, Memory, Mood, and Anxiety in Adults Over 50 Years of Age

Quick Facts

Study Start:2023-08-30
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05541887

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy
  2. * BMI (18.5-29.9)
  3. * Body weight ≥110 pounds
  1. * Pregnancy
  2. * Breast-feeding
  3. * Smokers
  4. * Diabetic
  5. * Heavy drinkers
  6. * Subjective but not clinically diagnosed cognitive impairment (Montreal cognitive assessment score \<26),
  7. * Inability to understand the cognitive function tasks
  8. * Intake of medication that might influence the outcome of the study (e.g. psychostimulant)
  9. * cannabis product user
  10. * Clinically diagnosed mental illnesses
  11. * Cardiovascular and neurological disorders
  12. * Uncontrolled hypertension

Contacts and Locations

Study Contact

Kylee Mai
CONTACT
479-203-8170
cmai1@ufl.edu
Liwei Gu, PhD
CONTACT
Lgu@ufl.edu

Principal Investigator

Liwei Gu, PhD
PRINCIPAL_INVESTIGATOR
University of Florida

Study Locations (Sites)

Food Science and human nutrition department at University of Florida
Gainesville, Florida, 32611
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Liwei Gu, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-30
Study Completion Date2025-06

Study Record Updates

Study Start Date2023-08-30
Study Completion Date2025-06

Terms related to this study

Additional Relevant MeSH Terms

  • Cognitive Performance
  • Memory
  • Mood
  • Anxiety