Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Description

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

Conditions

Cognitive Performance, Memory, Mood, Anxiety

Study Overview

Study Details

Study overview

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

Acute and Chronic Impacts of Muscadine Wine Polyphenols on Cognition, Memory, Mood, and Anxiety in Adults Over 50 Years of Age

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Condition
Cognitive Performance
Intervention / Treatment

-

Contacts and Locations

Gainesville

Food Science and human nutrition department at University of Florida, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy
  • * BMI (18.5-29.9)
  • * Body weight ≥110 pounds
  • * Pregnancy
  • * Breast-feeding
  • * Smokers
  • * Diabetic
  • * Heavy drinkers
  • * Subjective but not clinically diagnosed cognitive impairment (Montreal cognitive assessment score \<26),
  • * Inability to understand the cognitive function tasks
  • * Intake of medication that might influence the outcome of the study (e.g. psychostimulant)
  • * cannabis product user
  • * Clinically diagnosed mental illnesses
  • * Cardiovascular and neurological disorders
  • * Uncontrolled hypertension

Ages Eligible for Study

50 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Florida,

Liwei Gu, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

2025-06