RECRUITING

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.

Official Title

Longitudinal Prospective Study of Neurocognitive Outcomes and Multimodal Quantitative Neuroimaging Outcomes in Primary Brain Tumor Patients Receiving Brain Radiotherapy

Quick Facts

Study Start:2015-01
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05576103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Patients 18 years or older
  2. 2. Karnofsky performance status (KPS) ≥70
  3. 3. Life expectancy of ≥1 year
  4. 4. Primary brain tumor patients who will receive fractionated partial brain RT
  5. 5. Able to complete neurocognitive assessments
  1. 1. Inability to undergo MRI with contrast
  2. 2. Prior brain RT

Contacts and Locations

Study Contact

Sheila Medina
CONTACT
858-822-6575
s4medina@health.ucsd.edu
Jona Hattangadi-Gluth, MD
CONTACT

Study Locations (Sites)

Moores Cancer Center
San Diego, California, 92037
United States

Collaborators and Investigators

Sponsor: Jona Hattangadi-Gluth

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2015-01
Study Completion Date2026-12

Study Record Updates

Study Start Date2015-01
Study Completion Date2026-12

Terms related to this study

Additional Relevant MeSH Terms

  • Primary Brain Tumor
  • Glioma
  • Meningioma
  • Schwannoma