RECRUITING

Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research project is relevant to public health because both heart failure (HF) and mild cognitive impairment (e.g., trouble remembering and concentrating beyond normal aging) are highly prevalent among older adults in the United States. Despite advances in health care, there are no effective interventions for treating cognitive impairment in HF, which if left untreated, leads to suboptimal health, quality of life, and shorter survival. Therefore, the investigators propose to test the effect of a dual-component intervention comprised of a virtual reality-based cognitive restoration intervention and computerized cognitive training on cognitive function and overall health among 172 older adults with HF who experience mild cognitive impairment.

Official Title

Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

Quick Facts

Study Start:2023-04-18
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05601817

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. ≥ 55 years;
  2. 2. chronic HF Stage C validated from echocardiography or comparable measure or B-type natriuretic peptide (BNP) level \> 400 pg/ml \[or equivalent NT-proBNP\] in past 3 years;
  3. 3. ability to communicate in English;
  4. 4. capacity to consent according to the Indiana University Institutional Review Board policies, or lacks capacity to consent but has the ability to provide assent from someone who can serve as LAR; and
  5. 5. Subjectively reported cognitive concern assessed by the question, "Do you have any trouble with your memory or thinking?".
  1. 1. pre-HF (Stages A and B) or advanced HF (Stage D);
  2. 2. vision or hearing problems that can interfere with cognitive testing;
  3. 3. major neurological disorder (e.g., previously diagnosed dementia, Parkinson's disease, epilepsy, multiple sclerosis);
  4. 4. major psychiatric disease (e.g., schizophrenia, bipolar disorder);
  5. 5. life-threatening unstable illness other than HF (e.g., end-stage cancer); and
  6. 6. users of regular computerized cognitive training or participants in cognitive training trials in the past year.

Contacts and Locations

Study Contact

Miyeon Jung, PhD, RN
CONTACT
317-274-4360
miyjung@iu.edu

Study Locations (Sites)

Indiana University
Indianapolis, Indiana, 46202
United States

Collaborators and Investigators

Sponsor: Indiana University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-18
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2023-04-18
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • heart failure
  • mild cognitive impairment
  • older adults
  • cognitive intervention
  • cognitive training
  • attention restoration
  • virtual reality

Additional Relevant MeSH Terms

  • Heart Failure
  • Mild Cognitive Impairment