Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

Description

This research project is relevant to public health because both heart failure (HF) and mild cognitive impairment (e.g., trouble remembering and concentrating beyond normal aging) are highly prevalent among older adults in the United States. Despite advances in health care, there are no effective interventions for treating cognitive impairment in HF, which if left untreated, leads to suboptimal health, quality of life, and shorter survival. Therefore, the investigators propose to test the effect of a dual-component intervention comprised of a virtual reality-based cognitive restoration intervention and computerized cognitive training on cognitive function and overall health among 172 older adults with HF who experience mild cognitive impairment.

Conditions

Heart Failure, Mild Cognitive Impairment

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Study Overview

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Study Details

Study overview

This research project is relevant to public health because both heart failure (HF) and mild cognitive impairment (e.g., trouble remembering and concentrating beyond normal aging) are highly prevalent among older adults in the United States. Despite advances in health care, there are no effective interventions for treating cognitive impairment in HF, which if left untreated, leads to suboptimal health, quality of life, and shorter survival. Therefore, the investigators propose to test the effect of a dual-component intervention comprised of a virtual reality-based cognitive restoration intervention and computerized cognitive training on cognitive function and overall health among 172 older adults with HF who experience mild cognitive impairment.

Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure

Condition
Heart Failure
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Indiana University, Indianapolis, Indiana, United States, 46202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. ≥ 55 years;
  • 2. chronic HF Stage C validated from echocardiography or comparable measure or B-type natriuretic peptide (BNP) level \> 400 pg/ml \[or equivalent NT-proBNP\] in past 3 years;
  • 3. ability to communicate in English;
  • 4. capacity to consent according to the Indiana University Institutional Review Board policies, or lacks capacity to consent but has the ability to provide assent from someone who can serve as LAR; and
  • 5. Subjectively reported cognitive concern assessed by the question, "Do you have any trouble with your memory or thinking?".
  • 1. pre-HF (Stages A and B) or advanced HF (Stage D);
  • 2. vision or hearing problems that can interfere with cognitive testing;
  • 3. major neurological disorder (e.g., previously diagnosed dementia, Parkinson's disease, epilepsy, multiple sclerosis);
  • 4. major psychiatric disease (e.g., schizophrenia, bipolar disorder);
  • 5. life-threatening unstable illness other than HF (e.g., end-stage cancer); and
  • 6. users of regular computerized cognitive training or participants in cognitive training trials in the past year.

Ages Eligible for Study

55 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Indiana University,

Study Record Dates

2026-12-31