State Representation in Early Psychosis - Project 4

Eligibility Criteria

• * English proficiency, as determined by staff observation and participant self-report
• * Estimated IQ at or above 70, as estimated by the cognitive assessments
• * Clinical diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, psychosis NOS, bipolar disorder with psychosis, or major depressive disorder with psychosis; participants aged 36-45 must have onset of psychosis within the past 5 years
• * Achieved clinical stability, defined as outpatient status for at least one month prior to study participation
• * Unable or unwilling to provide informed consent
• * The participant is unable to demonstrate adequate decisional capacity, in the judgment of the consenting study staff member, to make a choice about participating in the research study
• * Participant is pregnant
• * Participant is illiterate
• * Cannot pass the CMRR Subject Safety Screen due to MRI contraindications
• * Presence of a major neurological disorder
• * Previous clinically significant head injury or prolonged unconsciousness, as determined by the PI/Co-Is
• * Meets criteria for substance or alcohol dependence within 3 months of enrollment
• * The presence of any major medical condition that, in the opinion of the PI/Co-Is, would impede participation in the study or would put the participant at additional risk by participating
• * Presence of severe alcohol or substance abuse
• * Has participated in significant formal cognitive training programs, as determined by the PI/Co-Is
• * Meets criteria for clinical risk of suicidal behavior, as defined by:
• * A suicide attempt within 6 months of enrollment
• * Active suicidal ideation at screening or baseline, as indicated by the C-SSRS
• * Previous intent to act on suicidal ideation with a specific plan and/or preparatory acts within 6 months of enrollment, as indicated by the C-SSRS
• * Meets DSM-5 criteria for psychotic, bipolar, or autism spectrum disorder
• * Has a family history (1st degree relative) of psychotic, bipolar, or autism spectrum disorder