RECRUITING

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

Description

The objective of this study is to measure the acceptability and impact of the progestin implant on frequency of vaso-occlusive crises, quality of life, and hematologic parameters in women with SCD.

Conditions

Sickle Cell Disease
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Related Conditions:

Sickle Cell Disease

Study Overview

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Study Details

Study overview

The objective of this study is to measure the acceptability and impact of the progestin implant on frequency of vaso-occlusive crises, quality of life, and hematologic parameters in women with SCD.

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

Condition
Sickle Cell Disease
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Penn Medicine University City, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Female aged 18-45
  • * Diagnosis of sickle cell disease (SS or SB0)
  • * Report of at least 1 vaso-occlusive pain episode per month on average in the previous 6 months
  • * Willing to discontinue any hormonal contraception at the time of enrollment. Washout period of 1 month required for all hormonal contraception prior to enrollment in the study.
  • * Access to a device with text messaging capability
  • * Must be able to read and understand English
  • * Willing to comply with study procedures
  • * SC Disease
  • * Use of Depo Provera in the past 6 months
  • * Changes to sickle cell medications in the past 3 months
  • * Contraindications to use of Nexplanon device as per clinical standards
  • * Currently pregnant or pregnant within the last month or seeking to become pregnant
  • * Currently breastfeeding

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Study Record Dates

2025-02-15