RECRUITING

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this study is to measure the acceptability and impact of the progestin implant on frequency of vaso-occlusive crises, quality of life, and hematologic parameters in women with SCD.

Official Title

Effects of the Contraceptive Implant in Women With Sickle Cell Disease

Quick Facts

Study Start:2023-06-08
Study Completion:2025-02-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05730205

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Female aged 18-45
  2. * Diagnosis of sickle cell disease (SS or SB0)
  3. * Report of at least 1 vaso-occlusive pain episode per month on average in the previous 6 months
  4. * Willing to discontinue any hormonal contraception at the time of enrollment. Washout period of 1 month required for all hormonal contraception prior to enrollment in the study.
  5. * Access to a device with text messaging capability
  6. * Must be able to read and understand English
  7. * Willing to comply with study procedures
  1. * SC Disease
  2. * Use of Depo Provera in the past 6 months
  3. * Changes to sickle cell medications in the past 3 months
  4. * Contraindications to use of Nexplanon device as per clinical standards
  5. * Currently pregnant or pregnant within the last month or seeking to become pregnant
  6. * Currently breastfeeding

Contacts and Locations

Study Contact

Arden McAllister, MPH
CONTACT
267-785-8044
arden.mcallister@pennmedicine.upenn.edu

Study Locations (Sites)

Penn Medicine University City
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-08
Study Completion Date2025-02-15

Study Record Updates

Study Start Date2023-06-08
Study Completion Date2025-02-15

Terms related to this study

Additional Relevant MeSH Terms

  • Sickle Cell Disease